Diabetes 1 Prevention

Diabetes 1 is a lethal type of diabetes if it left untreated, the patient is very depends on insulin. Until now, the exact cause of diabetes 1 is still unknown, but the doctors believe that there is connection with immunological origin.

There are many ways to avoid diabetes 1, such as:

Immunization

Diabetes type 1 is a form of diabetes mellitus that results from autoimmune destruction of insulin-producing beta cells of the pancreas. If a biochemical mechanism can be found that prevents the immune system from attacking beta cells, it may suggested to prevent or even stop the commencement of diabetes 1.

Several doctors try to make this into reality by causing the activation state of the immune system to change from Th1 state (“attack” by killer T Cells) to Th2 state (development of new antibodies).

BCG research

Dr. Denise Faustman, has theory by giving a cheap drugs that used to treat people with Mycobacterium tuberculosis called Bacillus Calmette-Guérin (BCG), would have the same effect to people with diabetes 1. Bacillus Calmette-Guérin (BCG) will stimulates TNF-α production, and it kills the white blood cells that responsible for destroying beta cells, and this prevents, or reverse diabetes 1.

TNF-α or Tumor necrosis factor-alpha, is part of the immune system that helps the immune system distinguish self from non-self tissue. People with type 1 diabetes are deficient in this substance, and with Bacillus Calmette-Guérin (BCG) Dr. Denise Faustman try to increase it. The trials for human have begun in 2008.

DiaPep277

DiaPep277 is a peptide fragment of a larger protein called HSP60, this substance has designed to cease the attacking beta cells, which is what diabetes 1. The product is currently being tested in people with latent autoimmune diabetes of adults (LADA).

Diamyd

Diamyd Medical also try to found a vaccine to fight diabetes 1, it called Diamyd. Injections with GAD65, an autoantigen involved in type 1 diabetes, has in clinical trials delayed the destruction of beta cells for at least 30 months, without serious adverse effects. Patients treated with the substance showed higher levels of regulatory cytokines, thought to protect the beta cells.

Main Article - Diabetes Cause

Diabetes Cause - Lifestyle

Do I get Diabetes? and Why?

Many of diabetes are caused by the uncontrollable lifestyle. Even some of them doesn't realize that they have diabetes, not until they checkup. A number of lifestyle factors are known to be important to the development of type 2 diabetes.

Gestational Diabetes

Gestational diabetes is diabetes type that occurs in women without previously diagnosed with this disease but having high blood glucose levels during pregnancy. Gestational diabetes affects 3%-10% of all pregnant women. It usually occurs at the 28th weeks or more of pregnancy. Most often, gestational diabetes goes away after the baby is born.

Gestational diabetes generally only has few symptoms and it is most commonly diagnosed by screening during pregnancy. Diagnostic tests detect inappropriately high levels of glucose in blood samples. No specific cause has been identified, but it is believed that the hormones produced during pregnancy increase a woman's resistance to insulin, resulting in impaired glucose tolerance.

Pre-diabetes

Pre-diabetes is a common condition that has connection with diabetes, however, the blood sugar level is high but not high enough to be considered as diabetes. Pre-diabetes increases your risk of developing type 2 diabetes and of heart disease or stroke. Many people destined to develop type 2 diabetes spend many years in a state of pre-diabetes which has been termed "America's largest healthcare epidemic."

Diabetes Treatment management

Diabetes treatment may include changing patient lifestyle that may include carefully managing diet, exercising, taking oral diabetes medication, using some form of insulin, maintaining proper circulation in extremities and may be further complicated by other external factors such as stress, illness, menses, injection site scarring, and other physiological factors unique to individual patients.

However, diabetes treatment may differ due to its types:

Diabetes type 1 Treatment Management

For diabetes type 1, the usual treatment is with insulin replacement therapy—usually by insulin injection or insulin pump, along with attention to dietary management, typically including carbohydrate tracking, and careful monitoring of blood glucose levels using glucose meters.

The most common insulins that use to treat diabetes type 1 nowadays are biosynthetic products produced using genetic recombination techniques; formerly, cattle or pig insulins were used, and even sometimes insulin from fish. A more recent trend of diabetes type 1 treatment, from several suppliers, is insulin analogs which are slightly modified insulins which have different onset of action times or duration of action times.

Diabetes Type 1 Symptoms-Signs

The subsequent lack of insulin leads to increased blood and urine glucose that makes diabetes type 1 lethal if left untreated, Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, and gums and teeth. Most people who develop diabetes type 1 are exceptionally healthy. Although the cause of type 1 diabetes is still not fully understood it is believed to be of immunological origin.

Type 1 diabetes takes only a few weeks to develop. The initial symptoms are:

• Frequent urination (polyuria).
  It’s all because the body tries to get rid of the excess glucose in the urine, diluting it with water
• Often feels thirsty (polydipsia)
• Fatigue
  

Diabetes type 2

Type-II Diabetes Mellitus makes insulin will not totally be missing, but the quantity will be less. The patients don’t have to depend on insulin from outside. It is treated as Non-insulin Dependent Diabetes Mellitus (NIDDM). Mostly middle aged or old people are prone to it, so it is called Adult onset Diabetes Mellitus. 80% of diabetic patients fall under this category.

In United States, 17.9 million people diagnosed with diabetes, 90% of whom are type 2. Diabetes traditionally considered a disease of adults, however, type 2 diabetes is increasingly diagnosed in children in parallel to rising obesity rates due to alterations in dietary patterns as well as in life styles during childhood.

Diabetes type 1

Diabetes type 1 is the promotion of insulin is totally stopped in the body. Forever these patients have to depend on insulin. The subsequent lack of insulin leads to increased blood and urine glucose. Small children are likely to get it. That's why it is also called Juvenile Diabetes Mellitus. Type 1 diabetes is fatal unless treated with insulin. Injection is the most common method of administering insulin; insulin pumps and inhaled insulin have been available at various times. Pancreas transplants have been used to treat type 1 diabetes; however, this procedure is currently still at the experimental trial stage.

Diabetes Diagnosis

Diabetes mellitus is a condition where blood glucose in high level, and later appear in urine. glucose test is the most important test to a diabetic. The fasting blood glucose level test is the most common screening diagnosis test for diabetes and pre-diabetes. It is usually ordered when someone has symptoms of diabetes or for a person having high diabetes risk factors.

These are diabetes diagnosis that often uses:

Diabetes Symptoms

Diabetes Mellitus is a condition which our body cells don't properly respond to the insulin that is produced. Insulin is a hormone produced in the pancreas which enables body cells to absorb glucose, to turn into energy.

Diabetes symptoms:

• Urinating often
• Getting thirst easily
• Feels hungry more often

Diabetes Types

Diabetes mellitus (DM) types are many, but there are three diabetes types that has simplified:

• Diabetes Mellitus type 1 (type 1 DM)
  It is characterized by loss of the insulin-producing beta cells of the islets of Langerhans in the pancreas leading to insulin deficiency. Type 1 diabetes can be further classified as immune-mediated or idiopathic.
  Type 1 diabetes has replaced several former terms, including:
• Childhood-onset diabetes
• Juvenile diabetes
• Insulin-dependent diabetes mellitus (IDDM)

Diabetes Mellitus

Diabetes is a group of metabolic diseases characterized by elevated of glucose in the blood (hyperglycemia) as a result of the body either not producing enough insulin, or because body cells do not properly respond to the insulin that is produced. Major sources of this glucose are absorption of ingested food in gastrointestinal tract and formation of glucose by the liver from food substance.

Insulin is a hormone produced by the pancreas and its job is to controls the level of glucose in the blood by regulating the production and storage of glucose. Insulin function is to enable body cells to absorb glucose, to turn into energy. If the body cells do not absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to various potential medical complications.