Diabetic Ketoacidosis

Diabetic Ketoacidosis (DKA) is a type of diabetes mellitus that makes the body cells are cannot to get glucose for energy due to low or no insulin secretion by the pancreas. And because of diabetic ketoacidosis, the body system cannot use glucose for energy and start breakdown stored fat for energy, however, this breakdown of fat produces toxic acid called ketones.

Diabetes 1 Prevention

Diabetes 1 is a lethal type of diabetes if it left untreated, the patient is very depends on insulin. Until now, the exact cause of diabetes 1 is still unknown, but the doctors believe that there is connection with immunological origin.

There are many ways to avoid diabetes 1, such as:

Immunization

Diabetes type 1 is a form of diabetes mellitus that results from autoimmune destruction of insulin-producing beta cells of the pancreas. If a biochemical mechanism can be found that prevents the immune system from attacking beta cells, it may suggested to prevent or even stop the commencement of diabetes 1.

Several doctors try to make this into reality by causing the activation state of the immune system to change from Th1 state (“attack” by killer T Cells) to Th2 state (development of new antibodies).

BCG research

Dr. Denise Faustman, has theory by giving a cheap drugs that used to treat people with Mycobacterium tuberculosis called Bacillus Calmette-Guérin (BCG), would have the same effect to people with diabetes 1. Bacillus Calmette-Guérin (BCG) will stimulates TNF-α production, and it kills the white blood cells that responsible for destroying beta cells, and this prevents, or reverse diabetes 1.

TNF-α or Tumor necrosis factor-alpha, is part of the immune system that helps the immune system distinguish self from non-self tissue. People with type 1 diabetes are deficient in this substance, and with Bacillus Calmette-Guérin (BCG) Dr. Denise Faustman try to increase it. The trials for human have begun in 2008.

DiaPep277

DiaPep277 is a peptide fragment of a larger protein called HSP60, this substance has designed to cease the attacking beta cells, which is what diabetes 1. The product is currently being tested in people with latent autoimmune diabetes of adults (LADA).

Diamyd

Diamyd Medical also try to found a vaccine to fight diabetes 1, it called Diamyd. Injections with GAD65, an autoantigen involved in type 1 diabetes, has in clinical trials delayed the destruction of beta cells for at least 30 months, without serious adverse effects. Patients treated with the substance showed higher levels of regulatory cytokines, thought to protect the beta cells.

Main Article - Diabetes Cause

Diabetes Cause - Lifestyle

Do I get Diabetes? and Why?

Many of diabetes are caused by the uncontrollable lifestyle. Even some of them doesn't realize that they have diabetes, not until they checkup. A number of lifestyle factors are known to be important to the development of type 2 diabetes.

Gestational Diabetes

Gestational diabetes is diabetes type that occurs in women without previously diagnosed with this disease but having high blood glucose levels during pregnancy. Gestational diabetes affects 3%-10% of all pregnant women. It usually occurs at the 28th weeks or more of pregnancy. Most often, gestational diabetes goes away after the baby is born.

Gestational diabetes generally only has few symptoms and it is most commonly diagnosed by screening during pregnancy. Diagnostic tests detect inappropriately high levels of glucose in blood samples. No specific cause has been identified, but it is believed that the hormones produced during pregnancy increase a woman's resistance to insulin, resulting in impaired glucose tolerance.

Pre-diabetes

Pre-diabetes is a common condition that has connection with diabetes, however, the blood sugar level is high but not high enough to be considered as diabetes. Pre-diabetes increases your risk of developing type 2 diabetes and of heart disease or stroke. Many people destined to develop type 2 diabetes spend many years in a state of pre-diabetes which has been termed "America's largest healthcare epidemic."

Diabetes Treatment management

Diabetes treatment may include changing patient lifestyle that may include carefully managing diet, exercising, taking oral diabetes medication, using some form of insulin, maintaining proper circulation in extremities and may be further complicated by other external factors such as stress, illness, menses, injection site scarring, and other physiological factors unique to individual patients.

However, diabetes treatment may differ due to its types:

Diabetes type 1 Treatment Management

For diabetes type 1, the usual treatment is with insulin replacement therapy—usually by insulin injection or insulin pump, along with attention to dietary management, typically including carbohydrate tracking, and careful monitoring of blood glucose levels using glucose meters.

The most common insulins that use to treat diabetes type 1 nowadays are biosynthetic products produced using genetic recombination techniques; formerly, cattle or pig insulins were used, and even sometimes insulin from fish. A more recent trend of diabetes type 1 treatment, from several suppliers, is insulin analogs which are slightly modified insulins which have different onset of action times or duration of action times.